C2H2
Description
Englbrecht et al. (2004): | C2H2 zinc fingers (ZF) display a wide range of functions, from DNA or RNA binding to the involvement in protein-protein interactions. Therefore ZFPs not only act in transcriptional regulation, either directly or through site-specific modification and/or regulation of chromatin, but also participate in RNA metabolism and in other cellular functions that probably require specific protein contacts of the ZF domain. |
References:
1) | Ciftci-Yilmaz, S; Mittler, R. 2008. The zinc finger network of plants. Cell. Mol. Life Sci. 65(7-8):1150-60 PubMed |
2) | Englbrecht, CC; Schoof, H; Böhm. S. 2004. Conservation, diversification and expansion of C2H2 zinc finger proteins in the Arabidopsis thaliana genome. BMC Genomics. 5(1):39 PubMed |
3) | Iuchi, S. 2001. Three classes of C2H2 zinc finger proteins. Cell. Mol. Life Sci. 58(4):625-35 PubMed |
4) | Lang, D; Weiche, B; Timmerhaus, G; Richardt, S; Riano-Pachon, DM; Correa, LG; Reski, R; Mueller-Roeber, B; Rensing, SA. 2010. Genome-wide phylogenetic comparative analysis of plant transcriptional regulation: a timeline of loss, gain, expansion, and correlation with complexity. Genome Biol Evol. 2: 488-503 PubMed |
5) | Takatsuji, H. 1999. Zinc-finger proteins: the classical zinc finger emerges in contemporary plant science. Plant Mol. Biol. 39(6):1073-8 PubMed |
Summary
Name: | C2H2 |
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Class: | TF |
Number of species containing the TAP: | 131 |
Number of available proteins: | 10535 |
The colour code corresponds to the rules for the domains:
should be contained
should not be contained
should not be contained
Domain rules:
(Domain names are clickable)
Phylogenetic tree for Archeaplastida:
No tree was calculated yet.
TAP distribution:
The following table shows the distribution of C2H2 over all species included in TAPscan. The values for e.g. a specific kingdom are shown in the tree below if you expand the tree for that kingdom.
Minimum | Maximum | Average | Median | Standard deviation |
---|---|---|---|---|
0 | 286 | 86.79 | 86.5 | 56.54 |