FHA

Description

Hofmann & Bucher (1995): The typical FHA domain comprises approximately 55-75 amino acids and contains three highly conserved blocks separated by more divergent spacer regions.

PFAM: The domain is present in a diverse range of proteins, such as kinases, phosphatases, kinesins, transcription factors, RNA-binding proteins and metabolic enzymes which partake in many different cellular processes - DNA repair, signal transduction, vesicular transport and protein degradation are just a few examples.

References:


1) Durocher, D; Jackson, SP. 2002. The FHA domain. FEBS Lett. 513(1):58-66 PubMed
2) Hofmann, K; Bucher, P. 1995. The FHA domain: a putative nuclear signalling domain found in protein kinases and transcription factors. Trends Biochem. Sci. 20(9):347-9 PubMed


Summary

Name: FHA
Class: TR
Number of species containing the TAP: 119
Number of available proteins: 1955

The colour code corresponds to the rules for the domains:

should be contained
should not be contained

Domain rules:


(Domain names are clickable)


Phylogenetic tree for Archeaplastida:

To view the tree click here.



TAP distribution:

The following table shows the distribution of FHA over all species included in TAPscan. The values for e.g. a specific kingdom are shown in the tree below if you expand the tree for that kingdom.

Minimum Maximum Average Median Standard deviation
06216.71510.37

List of species containing FHA sorted by kingdomcladesupergrouporderfamily:

hide all | show all

expand kingdom Archaeplastida (1987 proteins in 119 species)