GNAT
Description
| Vetting et al. (2005): | The Gcn5-related N-acetyltransferases are an enormous superfamily of enzymes that are universally distributed in nature and that use acyl-CoAs to acylate their cognate substrates. In this review, we will examine those members of this superfamily that have been both structurally and mechanistically characterized. These include aminoglycoside N-acetyltransferases, serotonin N-acetyltransferase, glucosamine-6-phosphate N-acetyltransferase, the histone acetyltransferases, mycothiol synthase, protein N-myristoyltransferase, and the Fem family of amino acyl transferases. |
References:
| Vetting, MW; S de Carvalho, LP; Yu, M; Hegde, SS; Magnet, S; Roderick, SL; Blanchard, JS. 2005. Structure and functions of the GNAT superfamily of acetyltransferases. Arch. Biochem. Biophys. 433(1):212-26 PubMed |
Summary
| Name: | GNAT |
|---|---|
| Class: | TR |
| Number of species containing the TAP: | 131 |
| Number of available proteins: | 4283 |
The colour code corresponds to the rules for the domains:
should be contained
should not be contained
should not be contained
Domain rules:
(Domain names are clickable)
Phylogenetic tree for Archeaplastida:
No tree was calculated yet.
TAP distribution:
The following table shows the distribution of GNAT over all species included in TAPscan. The values for e.g. a specific kingdom are shown in the tree below if you expand the tree for that kingdom.
| Minimum | Maximum | Average | Median | Standard deviation |
|---|---|---|---|---|
| 0 | 108 | 35.31 | 33 | 16.59 |