MADS

Description

Riechmann & Meyerowitz (1997): The MADS domain (MCM1, AGAMOUS, DEFICIENS, and SRF, serum response factor) is a conserved DNA-binding/dimerization region present in a variety of transcription factors from different kingdoms. MADS box genes represent a large multigene family in vascular plants. In angiosperms, many of the genes of the MADS family are involved in different steps of flower development, most notably in the determination of floral meristem and organ identity. The roles that MADS box genes play, however, are not restricted to control the development of the plant reproductive structures. The genetic, molecular, and biochemical basis of the action of the MADS domain proteins in the plant life cycle are reviewed here.

References:


1) Gramzow L.; Theissen G. 2010. A hitchhiker's guide to the MADS world of plants. Genome Biol. 11(6):214 PubMed
2) Jack, T. 2001. Plant development going MADS. Plant Mol. Biol. 46(5):515-20 PubMed
3) Nam, J; dePamphilis, CW; Ma, H; Nei, M. 2003. Antiquity and evolution of the MADS-box gene family controlling flower development in plants. Mol. Biol. Evol. 20(9):1435-47 PubMed
4) Nam, J; Kim, J; Lee, S; An, G; Ma, H; Nei, M. 2004. Type I MADS-box genes have experienced faster birth-and-death evolution than type II MADS-box genes in angiosperms. Proc. Natl. Acad. Sci. U.S.A. 101(7):1910-5 PubMed
5) Ng, M; Yanofsky, MF. 2001. Function and evolution of the plant MADS-box gene family. Nat. Rev. Genet. 2(3):186-95 PubMed
6) Riechmann, JL; Meyerowitz, EM. 1997. MADS domain proteins in plant development. Biol. Chem. 378(10):1079-101 PubMed
7) Shore, P; Sharrocks, AD. 1995. The MADS-box family of transcription factors. Eur. J. Biochem. 229(1):1-13 PubMed
8) West, AG; Sharrocks, AD. 1999. MADS-box transcription factors adopt alternative mechanisms for bending DNA. J. Mol. Biol. 286(5):1311-23 PubMed


Summary

Name: MADS
Class: TF
Number of species containing the TAP: 113
Number of available proteins: 4632

The colour code corresponds to the rules for the domains:

should be contained
should not be contained

Domain rules:


(Domain names are clickable)


Phylogenetic tree for Archeaplastida:

To view the tree click here.



TAP distribution:

The following table shows the distribution of MADS over all species included in TAPscan. The values for e.g. a specific kingdom are shown in the tree below if you expand the tree for that kingdom.

Minimum Maximum Average Median Standard deviation
026538.253142.27

List of species containing MADS sorted by kingdomcladesupergrouporderfamily:

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expand kingdom Archaeplastida (4705 proteins in 113 species)