|Okazaki et al. (1998):||In the fission yeast Schizosaccharomyces pombe, the onset of sexual development is controlled mainly by two external signals, nutrient starvation and mating pheromone availability. We have isolated a novel gene named rcd1+ as a key factor required for nitrogen starvation-induced sexual development. rcd1+ encodes a 283-amino-acid protein with no particular motifs. However, genes highly homologous to rcd1+ (encoding amino acids with >70% identity) are present at least in budding yeasts, plants, nematodes, and humans. Cells with rcd1+ deleted are sterile if sexual development is induced by nitrogen starvation but fertile if it is induced by glucose starvation. This results largely from a defect in nitrogen starvation-invoked induction of ste11+, a key transcriptional factor gene required for the onset of sexual development. The striking conservation of the gene throughout eukaryotes may suggest the presence of an evolutionarily conserved differentiation controlling system.|
|Okazaki, N; Okazaki, K; Watanabe, Y; Kato-Hayashi, M; Yamamoto, M; Okayama, H. 1998. Novel factor highly conserved among eukaryotes controls sexual development in fission yeast. Mol. Cell. Biol. 18(2):887-95 PubMed|
|Number of species containing the TAP:||116|
|Number of available proteins:||333|
The colour code corresponds to the rules for the domains:
should not be contained
(Domain names are clickable)
Phylogenetic tree for Archeaplastida:
To view the tree click here.
The following table shows the distribution of Rcd1-like over all species included in TAPscan. The values for e.g. a specific kingdom are shown in the tree below if you expand the tree for that kingdom.