Rcd1-like
Description
Okazaki et al. (1998): | In the fission yeast Schizosaccharomyces pombe, the onset of sexual development is controlled mainly by two external signals, nutrient starvation and mating pheromone availability. We have isolated a novel gene named rcd1+ as a key factor required for nitrogen starvation-induced sexual development. rcd1+ encodes a 283-amino-acid protein with no particular motifs. However, genes highly homologous to rcd1+ (encoding amino acids with >70% identity) are present at least in budding yeasts, plants, nematodes, and humans. Cells with rcd1+ deleted are sterile if sexual development is induced by nitrogen starvation but fertile if it is induced by glucose starvation. This results largely from a defect in nitrogen starvation-invoked induction of ste11+, a key transcriptional factor gene required for the onset of sexual development. The striking conservation of the gene throughout eukaryotes may suggest the presence of an evolutionarily conserved differentiation controlling system. |
References:
Okazaki, N; Okazaki, K; Watanabe, Y; Kato-Hayashi, M; Yamamoto, M; Okayama, H. 1998. Novel factor highly conserved among eukaryotes controls sexual development in fission yeast. Mol. Cell. Biol. 18(2):887-95 PubMed |
Summary
Name: | Rcd1-like |
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Class: | TR |
Number of species containing the TAP: | 127 |
Number of available proteins: | 333 |
The colour code corresponds to the rules for the domains:
should be contained
should not be contained
should not be contained
Domain rules:
(Domain names are clickable)
Phylogenetic tree for Archeaplastida:
No tree was calculated yet.
TAP distribution:
The following table shows the distribution of Rcd1-like over all species included in TAPscan. The values for e.g. a specific kingdom are shown in the tree below if you expand the tree for that kingdom.
Minimum | Maximum | Average | Median | Standard deviation |
---|---|---|---|---|
0 | 21 | 2.82 | 2 | 2.59 |