Guilfoyle et al. (1998): Auxin response factors or ARFs are a recently discovered family of transcription factors that bind with specificity to auxin response elements (AuxREs) in promoters of primary or early auxin-responsive genes. ARFs have an amino-terminal DNA-binding domain related to the carboxyl-terminal DNA-binding domain in the maize transactivator VIVIPAROUS1. All but one ARF identified to date contain a carboxyl-terminal protein-protein interaction domain that forms a putative amphipathic alpha-helix. A similar carboxyl-terminal protein-protein interaction domain is found in the Aux/IAA class of auxin-inducible proteins. Some ARFs contain transcriptional activation domains, while others contain repression domains. ARFs appear to play a pivotal role in auxin-regulated gene expression of primary response genes.


1) Guilfoyle, TJ; Ulmasov, T; Hagen, G. 1998. The ARF family of transcription factors and their role in plant hormone-responsive transcription. Cell. Mol. Life Sci. 54(7):619-27 PubMed
2) Ulmasov, T; Hagen, G; Guilfoyle, TJ. 1997. ARF1, a transcription factor that binds to auxin response elements. Science 276(5320):1865-8 PubMed


Name: ARF
Class: TF
Number of species containing the TAP: 94
Number of available proteins: 2277

The colour code corresponds to the rules for the domains:

should be contained
should not be contained

Domain rules:

(Domain names are clickable)

Phylogenetic tree for Archeaplastida:

To view the tree click here.

TAP distribution:

The following table shows the distribution of ARF over all species included in TAPscan. The values for e.g. a specific kingdom are shown in the tree below if you expand the tree for that kingdom.

Minimum Maximum Average Median Standard deviation

List of species containing ARF sorted by kingdomcladesupergrouporderfamily:

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expand kingdom Archaeplastida (2300 proteins in 94 species)