GNAT

Description

Vetting et al. (2005): The Gcn5-related N-acetyltransferases are an enormous superfamily of enzymes that are universally distributed in nature and that use acyl-CoAs to acylate their cognate substrates. In this review, we will examine those members of this superfamily that have been both structurally and mechanistically characterized. These include aminoglycoside N-acetyltransferases, serotonin N-acetyltransferase, glucosamine-6-phosphate N-acetyltransferase, the histone acetyltransferases, mycothiol synthase, protein N-myristoyltransferase, and the Fem family of amino acyl transferases.

References:


Vetting, MW; S de Carvalho, LP; Yu, M; Hegde, SS; Magnet, S; Roderick, SL; Blanchard, JS. 2005. Structure and functions of the GNAT superfamily of acetyltransferases. Arch. Biochem. Biophys. 433(1):212-26 PubMed


Summary

Name: GNAT
Class: TR
Number of species containing the TAP: 123
Number of available proteins: 4195

The colour code corresponds to the rules for the domains:

should be contained
should not be contained

Domain rules:


(Domain names are clickable)


Phylogenetic tree for Archeaplastida:

To view the tree click here.



TAP distribution:

The following table shows the distribution of GNAT over all species included in TAPscan. The values for e.g. a specific kingdom are shown in the tree below if you expand the tree for that kingdom.

Minimum Maximum Average Median Standard deviation
010835.2932.517.63

List of species containing GNAT sorted by kingdomcladesupergrouporderfamily:

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expand kingdom Archaeplastida (4341 proteins in 123 species)